[The influence of electrical stimulation of the paleocerebellar cortex upon spike-wave activity induced at the early stage of corazol-induced kindling in rats]

Autor: E V, Kobolev
Rok vydání: 2007
Předmět:
Zdroj: Patologicheskaia fiziologiia i eksperimental'naia terapiia. (4)
ISSN: 0031-2991
Popis: Chronic Wistar rats experiments have shown that repeated administrations of corazol in subthreshold dosages (30.0 mg/kg, i.p.) were followed by spike-wave (SW) bursts of discharges. Duration of such bursts as well as common period of their registration were longer in the course of epileptogen administration. High-frequency (100 Hz0 electric stimulation of the paleocerebellar cortex decreased duration of SW-complexes and period of their registration while low-frequency (10 Hz) electric stimulation resulted in a short-term effect of reduction of duration of SW bursts.
Databáze: OpenAIRE