Vascular permeability factor and vascular endothelial growth factor in ovarian hyperstimulation syndrome: a preliminary report

Autor:	J S, Krasnow, S L, Berga, D S, Guzick, A J, Zeleznik, K T, Yeo
Rok vydání:	1996
Předmět:	Adult Vascular Endothelial Growth Factor A Lymphokines Time Factors Vascular Endothelial Growth Factors Osmolar Concentration Endothelial Growth Factors Chorionic Gonadotropin Follicular Fluid Ovarian Hyperstimulation Syndrome Ovulation Induction Ascitic Fluid Humans Female Prospective Studies
Zdroj:	Fertility and sterility. 65(3)
ISSN:	0015-0282
Popis:	To determine whether serum levels of vascular permeability factor (VPF) are elevated in patients with ovarian hyperstimulation syndrome (OHSS) and to determine if luteinizing granulosa cells may be a source of VPF.Prospective observational study.University IVF and GIFT program.Eight consecutive IVF and GIFT patients at high risk for OHSS.Vascular permeability factor concentration in serum and follicular fluid.Serum VPF was significantly higher (15.2 +/- 4.0 pM; mean +/- SEM) on day +14 in the group who developed severe OHSS compared with those who did not. Follicular fluid VPF (171.5 +/- 18.5 pM) was approximately 100-fold greater than serum (1.7 +/- 1.3 pM) or peritoneal fluid (2.5 +/- 1.3 pM) 36 hours after hCG administration.Vascular permeability factor is elevated in patients with severe OHSS and the ovary may be a source of VPF secretion.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::233d11213ba9a9ca8b015d3e3d1cfd4f https://pubmed.ncbi.nlm.nih.gov/8774285 Zobrazit plný text záznamu