A role for 17-beta-estradiol in immunoendocrine regulation of murine cysticercosis (Taenia crassiceps)

Autor: L I, Terrazas, R, Bojalil, T, Govezensky, C, Larralde
Rok vydání: 1994
Předmět:
Zdroj: The Journal of parasitology. 80(4)
ISSN: 0022-3395
Popis: In experimental murine cysticercosis caused by Taenia crassiceps, parasite reproduction is favored by thymectomy or by orchidectomy, and restricted by ovariectomy. Hormonal reconstitution experiments showed that 17-beta-estradiol increases parasite numbers whereas 5-alpha-dihydrotestosterone was ineffective. Parasite numbers decreased with increments in cellular immunity but were insensitive to antibody levels. A possible immunoendocrinological interaction involving estrogen as a depressor of cellular immunity is envisaged in the control of cysticercosis.
Databáze: OpenAIRE