Enhanced periplasmic expression of human activin A in

Autor: Zahra, Hajihassan, Niloofar, Khairkhah, Farshid, Zandsalimi
Rok vydání: 2019
Předmět:
Zdroj: Preparative biochemistrybiotechnology. 50(2)
ISSN: 1532-2297
Popis: Activin A is a member of the transforming growth factor-beta (TGF-β) protein superfamily, which acts as a hormone in regulating cell proliferation and differentiation. Structurally, activin is a dimer of two subunits linked by a disulfide bond. Since the correct folding of this protein is essential for its function, we aimed to use a modified signal peptide to target the expressed recombinant protein to the periplasm of
Databáze: OpenAIRE