Enhanced periplasmic expression of human activin A in
Autor: | Zahra, Hajihassan, Niloofar, Khairkhah, Farshid, Zandsalimi |
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Rok vydání: | 2019 |
Předmět: | |
Zdroj: | Preparative biochemistrybiotechnology. 50(2) |
ISSN: | 1532-2297 |
Popis: | Activin A is a member of the transforming growth factor-beta (TGF-β) protein superfamily, which acts as a hormone in regulating cell proliferation and differentiation. Structurally, activin is a dimer of two subunits linked by a disulfide bond. Since the correct folding of this protein is essential for its function, we aimed to use a modified signal peptide to target the expressed recombinant protein to the periplasm of |
Databáze: | OpenAIRE |
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