| Autor: |
I D, Bespalova, V V, Kaliuzhin, N V, Riazantseva, Iu A, Mediantsev, I A, Osikhov, B Iu, Murashev |
| Rok vydání: |
2015 |
| Předmět: |
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| Zdroj: |
Klinicheskaia meditsina. 91(12) |
| ISSN: |
0023-2149 |
| Popis: |
To study pleiotropic effects of atorvastatin during 8-week therapy of metabolic syndrome and estimate their relationship with dynamics of quality of life characteristics (QLC).This 8-week study included 36 patients with stage II hypertensive disease associated with metabolic syndrome (MS). Comprehensive clinical, laboratory and instrumental examination was supplemented by QLC assessment using the MOS SF-36 questionnaire.8-week therapy of stage II hypertensive disease associated with metabolic syndrome using individually selected doses of atorvastatin (20 to 40 mg/d) significantly reduced atherogenic cholesterol fraction and serum leptin levels; it had positive effect on carbohydrate and purine metabolism and safely maintained positive dynamics of subjective assessment of most points of the MOS SF-36 questionnaire. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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