| Autor: |
Mariusz, Czechowski, Ewa, Karpel, Izabela, Duda, Konstancja, Grzybowska |
| Rok vydání: |
2009 |
| Předmět: |
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| Zdroj: |
Anestezjologia intensywna terapia. 40(1) |
| ISSN: |
0209-1712 |
| Popis: |
Respiratory distress and the need for mechanical ventilation, have been the most common reasons for ITU hospitalization. Pulmonary pathology is sometimes difficult to diagnose and differentiate; therefore we are on a continuous search for diagnostic tools and markers. It has been suggested that in patients intubated for acute lung injury, lower concentrations of surfactant proteins A and D in bronchoalveolar fluid and higher concentrations in the plasma are associated with more severe lung injury and worse clinical outcomes. Surfactant protein D (SP-D) plays a crucial role in defense mechanisms and immunomodulation, binding with various pathogens such as bacteria, fungi and viruses. SP-D is a valuable marker in ARDS and other specific and non-specific pulmonary pathologies, and may find a place as a valuable marker of the severity of disease. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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