| Autor: |
N B, Savel'eva, N Iu, Bykovskaia, M A, Dikunets, S L, Bolotov, G M, Rodchenkov |
| Rok vydání: |
2010 |
| Předmět: |
|
| Zdroj: |
Sudebno-meditsinskaia ekspertiza. 53(3) |
| ISSN: |
0039-4521 |
| Popis: |
The objective of this study was to demonstrate the possibility to use deuterated compounds as internal standards for the quantitative analysis of morphine by gas chromatography with mass-selective detection for the purpose of doping control. The paper is focused on the problems associated with the use of deuterated morphine-D3 as the internal standard. Quantitative characteristics of the calibration dependence thus documented are presented along with uncertainty values obtained in the measurements with the use of deuterated morphine-D6. An approach to the assessment of method bias associated with the application of morphine-D6 as the deuterated internal standard is described. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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