| Autor: |
N A, Mikhaĭlova, O V, Kuniagina, T N, Kuznetsova, A F, Sadykova, N S, Brodinova, G N, Bodrova |
| Rok vydání: |
1995 |
| Předmět: |
|
| Zdroj: |
Zhurnal mikrobiologii, epidemiologii i immunobiologii. (3) |
| ISSN: |
0372-9311 |
| Popis: |
The safety, reactogenicity and immunogenic activity of P. aeruginosa toxoid were studied in 46 volunteer donors. Systemic reactions to the injection of the preparation were absent in all vaccinees, in 2 subjects (4.3%) insignificant reactions at the site of injection in the form of hyperemia, sized 13-14 mm and disappearing within 48 hours, were registered. The preparation was found stimulate humoral immunity, which was manifested by an increase in the number of B-rosette-forming lymphocytes and the level of antitoxic IgG in the blood of the vaccinees. Besides, immune sera obtained from the blood of the volunteers were found to possess protective properties. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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