PI3K drives the de novo synthesis of coenzyme A from vitamin B5

Autor:	Christian C, Dibble, Samuel A, Barritt, Grace E, Perry, Evan C, Lien, Renee C, Geck, Sarah E, DuBois-Coyne, David, Bartee, Thomas T, Zengeya, Emily B, Cohen, Min, Yuan, Benjamin D, Hopkins, Jordan L, Meier, John G, Clohessy, John M, Asara, Lewis C, Cantley, Alex, Toker
Rok vydání:	2021
Předmět:	Lipid Metabolism Mass Spectrometry Pantothenic Acid Phosphotransferases (Alcohol Group Acceptor) Adenosine Triphosphate Acetyl Coenzyme A Metabolomics Coenzyme A Cysteine Phosphatidylinositol 3-Kinase Phosphorylation Proto-Oncogene Proteins c-akt Cell Proliferation Signal Transduction
Zdroj:	Nature. 608(7921)
ISSN:	1476-4687
Popis:	In response to hormones and growth factors, the class I phosphoinositide-3-kinase (PI3K) signalling network functions as a major regulator of metabolism and growth, governing cellular nutrient uptake, energy generation, reducing cofactor production and macromolecule biosynthesis
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::0b4b85ea68d475a44f61a5c11a3fe492 https://pubmed.ncbi.nlm.nih.gov/35896750 Zobrazit plný text záznamu Full text from SpringerLink