| Autor: |
W, Müller-Felber, M, Schmidt-Achert, D E, Pongratz |
| Rok vydání: |
1993 |
| Předmět: |
|
| Zdroj: |
Clinical neuropathology. 12(4) |
| ISSN: |
0722-5091 |
| Popis: |
Muscle biopsies of 9 children with congenital myotonic dystrophy were taken during the first year of life. All but one biopsy were abnormal showing nonspecific changes like an increased variability of fiber size, a selective atrophy of type I or type II fibers or an increased number of intrafusal muscle fibers. Nevertheless correct diagnosis of the disease based on morphological data only is impossible in some cases. A maturational arrest of the muscle is not a obligate feature of the disease. We conclude that muscle biopsy should be postponed after the first year of life. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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