Cytomegalovirus genomes demonstrated by polymerase chain reaction in synovial fluid from rheumatoid arthritis patients

Autor:	T, Murayama, F, Jisaki, M, Ayata, D, Sakamuro, T, Hironaka, K, Hirai, N, Tsuchiya, K, Ito, T, Furukawa
Rok vydání:	1992
Předmět:	Adult Aged 80 and over Male Base Sequence Molecular Sequence Data Cytomegalovirus Middle Aged Polymerase Chain Reaction Arthritis Rheumatoid Blotting Southern Cytomegalovirus Infections DNA Viral Osteoarthritis Synovial Fluid Humans Female Aged
Zdroj:	Clinical and experimental rheumatology. 10(2)
ISSN:	0392-856X
Popis:	Synovial fluid from 20 patients with rheumatoid arthritis was analyzed to detect human cytomegalovirus (CMV) genomic material using polymerase chain reaction. Of 20 samples tested, 9 were positive for CMV by either ethidium bromide staining or Southern blotting. In contrast, CMV was detected in only 2 of 18 control patients with osteoarthritis. These results suggest an etiologic relationship between CMV and rheumatoid arthritis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::03193b09dc2bb592e3fd06ff85b57cbf https://pubmed.ncbi.nlm.nih.gov/1324125 Zobrazit plný text záznamu