| Autor: |
Sergio, Vela-Avitúa, Ingunn, Thorland, Vasileios, Bakopoulos, Kantham, Papanna, Arkadios, Dimitroglou, Eleftherios, Kottaras, Papaharisis, Leonidas, Bruno, Guinand, Costas S, Tsigenopoulos, Muhammad L, Aslam |
| Rok vydání: |
2021 |
| Zdroj: |
Frontiers in genetics. 13 |
| ISSN: |
1664-8021 |
| Popis: |
Viral nervous necrosis (VNN) is an infectious disease caused by the red-spotted grouper nervous necrosis virus (RGNNV) in European sea bass and is considered a serious concern for the aquaculture industry with fry and juveniles being highly susceptible. To understand the genetic basis for resistance against VNN, a survival phenotype through the challenge test against the RGNNV was recorded in populations from multiple year classes (YC2016 and YC2017). A total of 4,851 individuals from 181 families were tested, and a subset (n∼1,535) belonging to 122 families was genotyped using a ∼57K Affymetrix Axiom array. The survival against the RGNNV showed low to moderate heritability with observed scale estimates of 0.18 and 0.25 obtained using pedigree vs. genomic information, respectively. The genome-wide association analysis showed a strong signal of quantitative trait loci (QTL) at LG12 which explained ∼33% of the genetic variance. The QTL region contained multiple genes ( |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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