The Efficacy of Alone or Combined Treatment of Aglepristone and Cabergoline on Termination of Mid-term Pregnancy in Cats([1][2])

Autor: Ay, Serhan Serhat, Onyay, Firdevs, Saral, Gulsah, Kaya, Duygu, Aslan, Selim, Findik, Murat
Přispěvatelé: OMÜ
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Popis: FINDIK, Murat/0000-0003-1408-2548 WOS: 000440196100002 This study determined the efficacy of a combination of aglepristone and cabergoline on termination of mid-term cat pregnancies. Twenty cats with unwanted pregnancies between 30-40 days were included in the study Aglepristone (10 mg/kg, sc) was given to the AGL group (n=6) twice in a 24-h interval. Cabergoline (5 mu g/kg, peros) was administered to the CBG group (n=7) once daily until abortion started or for 8 days. AGL+CBG (n=7) received a combined treatment with both drugs. Abortion occurred in 50% of cats in the AGL group, 71.4% in the CBG group, and 100% in the AGL+CBG. However, the completion of pregnancy termination rate was 85.7% because of fetal retention in one cat from the AGL+CBG group. The interval between treatment-start of abortion (T-SA) was shorter in the AGL+CBG group (3.6 +/- 0.3 days) than in the AGL (6.5 +/- 0.0) and CBG (6.2 +/- 0.2) groups (P
Databáze: OpenAIRE