Design, synthesis, in vitro biological evaluation and anti-biofilm activity of new beta-lactam and linezolid-like compounds as potential antibacterial agents against Staphylococcus aureus infections in cystic fibrosis patients

Autor: R. Musumeci, C. E. Cocuzza, C. Colombo, L. Cariani, L. Garlaschi, GALLETTI, PAOLA, TOLOMELLI, ALESSANDRA, GENTILUCCI, LUCA, GIACOMINI, DARIA
Přispěvatelé: FONDAZIONE FIBROSI CISTICA, R. Musumeci, C. E. Cocuzza, C. Colombo, L. Cariani, L. Garlaschi, P. Galletti, A. Tolomelli, L. Gentilucci, D. Giacomini
Jazyk: angličtina
Rok vydání: 2011
Předmět:
Popis: The emergence of multidrug-resistant bacteria, such as MRSA, poses a special challenge in the treatment of infections in CF and new therapeutic agents are required. The aim of this project was the design, synthesis and evaluation of the “in vitro” activity of new antistaphylococcal agents against recent well characterized antibiotic-resistant and virulent strains of S. aureus isolated from children with CF.
Databáze: OpenAIRE