| Autor: |
Villena, Julio Cesar, Vizoso Pinto, María Guadalupe, Rodriguez, Ana Virginia, Salva, Maria Susana, Alvarez, Gladis Susana, Kitazawa, Haruki |
| Přispěvatelé: |
Méndez Vilas, Antonio |
| Jazyk: |
angličtina |
| Rok vydání: |
2013 |
| Předmět: |
|
| Zdroj: |
Microbial pathogens and strategies for combating them: science, technology and education |
| Popis: |
Viruses are the most important cause of severe mucosal infections worldwide especially in high risk populations such as in infants, young children, elderly and immunocompromised hosts. A significant improvement in the knowledge of how the host immune response contributes to the pathogenesis of viral infections has been made during the last decade. This understanding of host response and molecular pathogenesis of viral infections has been critical for the development of vaccines, antivirals and other disease intervention approaches such as probiotic functional foods. Lactic acid bacteria (LAB) are technologically and commercially important and have various beneficial effects on human health. Several studies have demonstrated that certain LAB strains can exert their beneficial effect on the host through their immunomudulatory activity. These strains, termed immunobiotics, have been used for the development of probiotic foods with the ability to stimulate mucosal antiviral immunity. In this review we examine the current scientific literature concerning the advances in our understanding of how commensal microorganisms are able to modulate intestinal viral immunity and affect the outcome of viral diseases. Research from the last decade demonstrates that immunobiotic LAB represent a promising resource for the development of prevention strategies against viral infections that could be effective tools for medical application. Fil: Villena, Julio Cesar. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Centro de Referencia para Lactobacilos; Argentina. Tohoku University; Japón Fil: Vizoso Pinto, María Guadalupe. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto Superior de Investigaciones Biológicas. Universidad Nacional de Tucumán. Instituto Superior de Investigaciones Biológicas; Argentina Fil: Rodriguez, Ana Virginia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Centro de Referencia para Lactobacilos; Argentina Fil: Salva, Maria Susana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Centro de Referencia para Lactobacilos; Argentina Fil: Alvarez, Gladis Susana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Centro de Referencia para Lactobacilos; Argentina. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia. Instituto de Bioquímica Aplicada; Argentina Fil: Kitazawa, Haruki. Tohoku University; Japón |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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