Influência dos fatores de risco tradicionais e não-tradicionais na prevalência da doença renal do diabetes no diabetes tipo 1
| Autor: | Pizarro, Marcela Haas |
|---|---|
| Přispěvatelé: | Gomes, Marilia de Brito, Bregman, Rachel, Pôrto, Luís Cristóvão de Moraes Sobrino, Carneiro, João Régis Ivar |
| Jazyk: | portugalština |
| Rok vydání: | 2019 |
| Předmět: |
Doença renal do diabetes
Self-reported color race Genomic ancestry Diabetes tipo 1. Ácido úrico Genética de populações urologic and male genital diseases Ancestralidade genômica Type 1 diabetes Nefropatias diabéticas Diabetes mellitus tipo 1 Ácido úrico Rins doença Cor auto-referida CIENCIAS DA SAUDE::MEDICINA::CLINICA MEDICA::ENDOCRINOLOGIA [CNPQ] Diabetic kidney disease Uric acid |
| Zdroj: | Biblioteca Digital de Teses e Dissertações da UERJ Universidade do Estado do Rio de Janeiro (UERJ) instacron:UERJ |
| Popis: | Submitted by Boris Flegr (boris@uerj.br) on 2021-01-06T20:52:31Z No. of bitstreams: 1 Marcela Haas Pizarro Tese completa.pdf: 3447949 bytes, checksum: 138ce5e331644c71b5491ffba3f5c567 (MD5) Made available in DSpace on 2021-01-06T20:52:31Z (GMT). No. of bitstreams: 1 Marcela Haas Pizarro Tese completa.pdf: 3447949 bytes, checksum: 138ce5e331644c71b5491ffba3f5c567 (MD5) Previous issue date: 2019-09-10 This dissertation analyses the association between the presence of chronic kidney disease (CKD) and elevated serum uric acid levels, self-reported color race, and genomic ancestry in patients with type 1 diabetes. This dissertation includes two articles, both analyzing data from multicenter, cross-sectional studies, with patients from all geographic areas of Brazil, that initially included 1760 patients. The studies used questionnaires to collect clinical data of the patients, as well as a clinical examination with the evaluation of anthropometric data and laboratory tests. Renal function was estimated by the CKD-EPI formula in adults and was expressed as the glomerular filtration rate (GFR). Albuminuria concentration was measured from a morning urine sample. The presence of albuminuria was defined as albuminuria ≥ 30mg/dl. The studies divided the patients into two groups: Normal renal function group (GFR ≥ 60 ml/min and the absence of albuminuria) and the CKD group (GFR |
| Databáze: | OpenAIRE |
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