| Autor: |
Béresniak, Ariel, Rizzo, Caterina, Oxford, John S., Goryński, Paweł, Pistol, Adriana, Fabiani, Massimo, Napoli, Christian, Barral, Marta, Niddam, Laurent, Bounekkar, Ahmed, Bonnevay, Stéphane, Lionis, Christos D. |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Popis: |
Background: The FLURESP project is a public health project funded by the European Commission with the objective to design a methodological approach in order to compare the cost-effectiveness of existing public health measures against human influenza pandemics in four target countries: France, Italy, Poland and Romania. This article presents the results relevant to the French health system using a data set specifically collected for this purpose. Methods: Eighteen public health interventions against human influenza pandemics were selected. Additionally, two public-health criteria were considered: ‘achieving mortality reduction ≥40%’ and ‘achieving morbidity reduction ≥30%’. Costs and effectiveness data sources include existing reports, publications and expert opinions. Cost distributions were taken into account using a uniform distribution, according to the French health system. Results: Using reduction of mortality as an effectiveness criterion, the most cost-effective options was ‘implementation of new equipment of Extracorporeal membrane oxygenation (ECMO) equipment’. Targeting vaccination to health professionals appeared more cost-effective than vaccination programs targeting at risk populations. Concerning antiviral distribution programs, curative programs appeared more cost-effective than preventive programs. Using reduction of morbidity as effectiveness criterion, the most cost-effective option was ‘implementation of new equipment ECMO’. Vaccination programs targeting the general population appeared more cost-effective than both vaccination programs of health professionals or at-risk populations. Curative antiviral programs appeared more cost-effective than preventive distribution programs, whatever the pandemic scenario. Conclusion: Intervention strategies against human influenza pandemics impose a substantial economic burden, suggesting a need to develop public-health cost-effectiveness assessments across countries. © The Author(s) 2019. Published by Oxford University Press on behalf of the European Public Health Association. All rights reserved. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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