The DIAMORFOSIS (DIAgnosis and Management Of lung canceR and FibrOSIS) survey: international survey and call for consensus

Autor: Tzouvelekis, Argyris Antoniou, Katerina Kreuter, Michael and Evison, Matthew Blum, Torsten G. Poletti, Venerino Grigoriu, Bogdan Vancheri, Carlo Spagnolo, Paolo Karampitsakos, Theodoros Bonella, Francesco Wells, Athol Raghu, Ganesh and Molina-Molina, Maria Culver, Daniel A. Bendstrup, Elisabeth and Mogulkoc, Nesrin Elia, Stefano Cadranel, Jacques Bouros, Demosthenes
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Popis: Background: Currently there is major lack of agreement on the diagnostic and therapeutic management of patients with idiopathic pulmonary fibrosis (IPF) and lung cancer. Our aim was to identify variations in diagnostic and management strategies across different institutions and provide rationale for a consensus statement on this issue. Methods: This was a joint-survey by European Respiratory Society (ERS) Assemblies 8, 11 and 12. The survey consisted of 25 questions. Results: Four hundred and ninety-four (n=494) physicians from 68 different countries and five continents responded to the survey. Ninety-four per cent of participants were pulmonologists, 1.8% thoracic surgeons and 1.9% oncologists; 97.7% were involved in multidisciplinary team approaches on diagnosis and management. Regular low-dose high-resolution computed tomography (HRCT) scan was used by 49.5% of the respondents to screen for lung cancer in IPF. Positron emission tomography (PET) scan and endobronchial ultrasound (EBUS) is performed by 60% and 88% to diagnose nodular lesions with mediastinal lymphadenopathy in patients with advanced and mild IPF, respectively. Eighty-three per cent of respondents continue anti-fibrotics following lung cancer diagnosis; safety precautions during surgical interventions including low tidal volume are applied by 67%. Stereotactic radiotherapy is used to treat patients with advanced IPF (diffusing capacity of the lung for carbon monoxide (DLCO)
Databáze: OpenAIRE