Repeated leftover serosurvey of sars-cov-2 igg antibodies in greece, may to august 2020

Autor: Bogogiannidou, Z. Speletas, M. Vontas, A. Nikoulis, D.J. Dadouli, K. Kyritsi, M.A. Mouchtouri, V.A. Mina, P. Anagnostopoulos, L. Koureas, M. Karavasilis, V. Nikou, O. Pinaka, O. Thomaidis, P.C. Kadoglou, K. Bedevis, K. Spyrou, N. Eleftheriou, A.A. Papaevangelou, V. Gikas, A. Vatopoulos, A. Ntzani, E.E. Prezerakos, P. Tsiodras, S. Hadjichristodoulou, C.
Jazyk: angličtina
Rok vydání: 2021
Popis: A serosurvey of IgG antibodies against SARS-CoV-2 was conducted in Greece between May and August 2020. It was designed as a cross-sectional survey and was repeated at monthly intervals. The leftover sampling methodology was used and a geographically stratified sampling plan was applied. Of 20,110 serum samples collected, 89 (0.44%) were found to be positive for anti-SARS-CoV-2 antibodies, with higher seroprevalence (0.35%) observed in May 2020. The highest seroprevalence was primarily observed in the “30–49” year age group. Females presented higher seroprevalence compared to males in May 2020 (females: 0.58% VS males: 0.10%). This difference reversed during the study period and males presented a higher proportion in August 2020 (females: 0.12% VS males: 0.58%). Differences in the rate of seropositivity between urban areas and the rest of the country were also observed during the study period. The four-month infection fatality rate (IFR) was estimated to be 0.47%, while the respective case fatality rate (CFR) was at 1.89%. Our findings confirm low seroprevalence of COVID-19 in Greece during the study period. The young adults are presented as the most affected age group. The loss of the cumulative effect of seropositivity in a proportion of previous SARS-CoV-2 infections was indicated. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.
Databáze: OpenAIRE