| Autor: |
Tolia, Maria Verganelakis, Dimitrios Tsoukalas, Nikolaos and Kyrgias, George Papathanasiou, Matilda Mosa, Eftichia and Kokakis, Ioannis Kouvaris, John R. Pissakas, George and Pistevou-Gombaki, Kyriaki Kelekis, Nikolaos Kouloulias, Vasileios |
| Jazyk: |
angličtina |
| Rok vydání: |
2015 |
| Popis: |
Purpose. We studied the prognostic significance of Magnetic Resonance Spectroscopy (MRS) in operated high grade gliomas. Materials and Methods. Twelve patients were treated with radiotherapy and Temozolomide. The MRS data were taken four weeks after operation (before radiotherapy) and every six months after the completion of RT. The N-acetyl aspartate, choline, creatine, and myo-inositol parameters were quantified, analyzed, and correlated to recurrence-free survival (RFS). Results. The median RFS was 26.06 months. RFS was significantly worse in elderly patients (P = 0.001) along with the higher choline/creatine ratios at either baseline (P = 0.003) or six months post Radiotherapy (P = 0.042). Median RFS was 23 months in high choline/creatine levels = 2 at 6 months after radiotherapy and 11 months for those with |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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