| Autor: |
Politou, Marianna Koutras, Dimitrios Kaparos, Georgios and Valsami, Serena Pittaras, Theodoros Logothetis, Emmanouil and Panayiotakopoulos, George Kouskouni, Evangelia |
| Jazyk: |
angličtina |
| Rok vydání: |
2014 |
| Předmět: |
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| Popis: |
Background: Herpes viruses infection transmitted through healthy but infected blood donors pose a danger to herpes-naive immunocompromised recipients. The risk of transfusion-related HHV-8 transmission is different in endemic and not endemic areas. HHV-6 and HHV-8 seroprevalence and viral load among blood donors have been reported from different countries. The aim of our study was to assess the seroprevalence of HHV-8 and HHV-6 in volunteer blood donors from Greece which is unknown. Findings: Serum samples from 179 healthy blood donors were tested for the presence of IgG antibodies against HHV-6 and HHV-8 with ELISA. None of the 179 donors of Greek origin tested was positive for HHV-8. HHV-6 seropositivity was assessed in 160 blood donors’ samples and was found to be 78.75% ( 126/160). The HHV-6 seroprevalence did not differ either between males and females or among different decade age groups. Conclusions: The fact, that no blood donor was positive for HHV-8 IgG antibodies indicates that the risk for transfusion related HHV-8 transmission in Greece, if any, is negligible and does not warrant broad testing for HHV-8. Definitely further studies are needed, in order to clarify the potential risk of HHV-6 transmission. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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