| Autor: |
Tomiyama, H. Vlachopoulos, C. Xaplanteris, P. Nakano, H. Shiina, K. Ishizu, T. Kohro, T. Higashi, Y. Takase, B. Suzuki, T. Yamazaki, T. Furumoto, T. Kario, K. Inoue, T. Koba, S. Takemoto, Y. Hano, T. Sata, M. Ishibashi, Y. Node, K. Tanaka, A. Maemura, K. Ohya, Y. Furukawa, T. Ito, H. Ohkuma, T. Ninomiya, T. Chikamori, T. Yamashina, A. Ueda, S.-I. |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
|
| Popis: |
The score based on the office systolic blood pressure, age, fasting blood glucose level, and estimated glomerular filtration rate (SAGE score) has been proposed as a useful marker to identify elevated values of carotid-femoral pulse wave velocity (PWV). The present cross-sectional study was conducted to examine whether the SAGE score is also a useful marker to identify subjects with elevated brachial-ankle PWV values in Japanese subjects with hypertension. We measured the brachial-ankle PWV and calculated the SAGE score in a total of 1019 employees of a Japanese company with hypertension and 817 subjects with hypertension derived from a multicenter study cohort. The analyses in this study were based on data from these two study groups as well as on a composite population of the two (n = 1836). The receiver operating characteristic curve analysis showed that the area under the curve to identify subjects with brachial-ankle PWV values of ≥1800 cm/s was over 0.70 in each of the three study groups. Even after adjustments, a SAGE score ≥7 had a significant odds ratio for identifying subjects with brachial-ankle PWV values ≥1800 cm/s in the 1836 study subjects from the composite occupational and multicenter study cohort (odds ratio = 2.1, 95% confidence interval = 1.4–3.0, P < 0.01). Thus, in Japanese subjects with hypertension, the SAGE score may be a useful marker for identifying subjects with elevated brachial-ankle PWV values. © 2020, The Japanese Society of Hypertension. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
