Résultats d'un programme de transplantation hépatique combiné adultes-enfants en Suisse
| Autor: | Mentha, Gilles, Le Coultre, Claude Pierrette, Giostra, Emiliano, Belli, Dominique Charles, Huber, Olivier, Rubbia-Brandt, Laura, Hadengue, Antoine, Morel, Philippe |
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| Jazyk: | francouzština |
| Rok vydání: | 1999 |
| Předmět: |
ddc:616
Adult Liver Diseases/classification/surgery Reoperation ddc:618 Time Factors ddc:617 Liver Transplantation/mortality/physiology/statistics & numerical data Tissue and Organ Procurement/organization & administration ddc:616.07 Graft Rejection/epidemiology Europe Survival Rate surgical procedures operative Postoperative Complications Humans Registries Child Switzerland Retrospective Studies |
| Zdroj: | Schweizerische medizinische Wochenschrift, Vol. 129, No 11 (1999) pp. 433-40 |
| ISSN: | 0036-7672 |
| Popis: | Between July 1987 and August 1998, 173 orthotopic liver transplantations (OLT) were performed in Geneva. We studied a homogeneous group of 114 OLT performed during the 6 years between 1992 and 1997 on 107 patients (89 adults and 18 children; 7 retransplantations). Although Geneva has the largest transplantation programme in Switzerland and is the only centre performing paediatric liver transplantation, the mean number of procedures per year was 19, corresponding to only a small transplantation programme in Europe. It could be reasonably questioned, therefore, whether Swiss patients are not at a disadvantage as compared with patients from European countries with larger liver transplantation centres. Although the perioperative morbidity was still considerable, the results of this series -90% of actuarial patient survival at 1 and 2 years and 84% at 5 years-compare favourably with the results of the European Liver Transplantation Registry: 76% of actuarial patient survival at 1 year and 65% at 5 years. In this series, 95 patients (89%) were alive on January 1, 1998. As no patient was refused on the severity of the liver disease and as more than 10% of OLT were performed as emergencies, a bias due to the selection of the best cases cannot explain the good results. This series demonstrates that a small liver transplantation centre may obtain results that compare favourably with the results of large European centres, and that Swiss patients are not at a disadvantage as compared with patients of other European countries. |
| Databáze: | OpenAIRE |
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