A new antibacterial pyridinoside from a Streptomyces species

Autor:	Barman, Ranjan K., Gafur, Mohammad A., Rahman, Bytul M., Khondkar, Proma
Jazyk:	angličtina
Rok vydání:	2010
Předmět:	antibacterial activity 8-propionate-2-β-(D+)-glucosyl-9 10-pyranopyridine Streptomyces species Farmacología bacteria Bacterias gram-positivas Farmacia Bacterias
Popis:	A new compound, 8-propionate-2-β-(D+)-glucosyl-9,10-pyranopyridine, was isolated from the chloroform extract of a Streptomyces species. The structure of the compound was confirmed by spectroscopic techniques including UV, IR, HR-ESI-MS, 1H-NMR, 13C-NMR, 1H-1H COSY and HMBC (long range coupling) spectra. The compound showed significant antibacterial activity against Gram-positive bacteria. The minimum inhibitory concentrations (MIC) of the isolated compound against Bacillus megaterium, Streptococcus β-haemolyticus, Bacillus subtilis, Escherichia coli, Salmonella typhi and Shigella dysenteriae were found to be 0.16, 0.08, 0.08, 0.04, 0.08 and 0.08 μM, respectively. Colegio de Farmacéuticos de la Provincia de Buenos Aires
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=od______1329::40ecc9f40e02c3340a1071ec100aa606 http://sedici.unlp.edu.ar/handle/10915/7949 Zobrazit plný text záznamu