EFFECTS OF ANTIEPILEPTIC DRUGS ON THE LEVEL OF PHYSICAL ACTIVITY IN PATIENTS WITH EPILEPSY

Autor: ZAVOREO, IRIS, TESKERA, MARGARETA, CILIGA, DUBRAVKA, TROŠT BOBIĆ, TATJANA, PETRINOVIĆ, LIDIJA, BAŠIĆ KES, VANJA
Jazyk: chorvatština
Rok vydání: 2021
Předmět:
Zdroj: Acta medica Croatica : Časopis Akademije medicinskih znanosti Hrvatske
Volume 75
Issue 2
ISSN: 1848-8897
1330-0164
Popis: Cilj ovog istraživanja bio je ispitati utjecaj antiepileptične terapije na razinu tjelesne aktivnosti kod osoba s epilepsijom. Uzorak ispitanika činilo je 140 osoba oboljelih od epilepsije, 73 muškarac i 67 žena prosječne dobi od 24 do 45 godina (35,15 ± 10,01), a istraživanje je provedeno na Klinici za neurologiju KBC-a Sestre milosrdnice u Zagrebu. Testiranje se provodilo upitnikom International Physical Activity Questionnaire (IPAQ), koji je sadržavao 5 varijabli: posao, prijevoz, kućanski poslovi i briga za obitelj, sport i sportska rekreacija, vrijeme provedeno sjedeći. Korištene su i varijable o trajanju bolesti, učestalosti napada, vrsti epileptičnog napada te vrsti liječenja koje su dio općih podataka iz dokumentacije ispitanika. Dobiveni rezultati pokazuju kako je najčešća niska razina tjelesne aktivnosti (TA) kod osoba sa statusom nezaposlen, koji boluju više od 15 godina i imaju više od 15 napada tijekom godine. Kod osoba s generaliziranim napadima također je zabilježena niska razina TA, a visoka kod osoba sa žarišnim napadima. Muškarci za razliku od žena češće bilježe visoku razinu TA kao i zaposlene osobe. Bolesnici liječeni monoterapijom češće prakticiraju višu razinu TA za razliku od onih koji u svom liječenju koriste dva i/ili više antiepileptika (politerapija), gdje je zabilježena niska razina TA.
The objective of this study was to examine the effects of antiepileptic drugs on the level of physical activity in people with epilepsy. We included 140 patients suffering from epilepsy, 73 men and 67 women, average age 24-45 years (35.15± 10.01). The study was conducted at Sestre milosrdnice University Hospital Centre, Department of Neurology in Zagreb. The patients were evaluated by the International Physical Activity Questionnaire (IPAQ) that comprises of 5 domains: work, transport, household chores, and care for the family, sporting activities and recreation, as well as sedentary time. The variable of disease duration was also used, as well as the variables of the seizure incidence, type of epileptic seizures, and type of treatment, which are included in general information provided in medical documentation. According to the findings, unemployed persons suffering from epilepsy for over 15 years with over 15 seizures throughout the year most frequently showed low levels of physical activity. Low levels of physical activity were also identified in persons with generalized seizures, whereas persons with focal seizures showed high levels of physical activity. Men and employed persons more frequently showed high levels of physical activity as opposed to women. Patients on monotherapy more frequently showed higher levels of physical activity as compared with those using more than two antiepileptic drugs, i.e. those on polytherapy, who showed low levels of physical activity.
Databáze: OpenAIRE
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