Isolated Maternal Hypothyroxinemia and Its Perinatal Outcome in North Macedonia
| Autor: | Avramovska, Maja, Karanfilski, Borislav, Dimitrov, Goran, Dzikova, Elena, Daneva Markova, Ana, Hadzi Lega, Marija, Tofoski, Gligor, Sikole, Aleksandar |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Acta clinica Croatica Volume 60. Issue 2. |
| ISSN: | 1333-9451 0353-9466 |
| Popis: | Isolated maternal hypothyroxinemia (IMH) is defined as the presence of low maternal total thyroxine (TT4) level in conjunction with normal maternal thyroid-stimulating hormone (TSH) level. The aim was to investigate whether IMH is associated with adverse pregnancy outcome in North Macedonia. Dried blood spot samples were obtained from 359 pregnant women meeting the inclusion criteria and analyzed for TT4 and TSH. Postpartum data were entered from their medical histories. Out of 359 women, 131 (37.42%) belonged to IMH group. There were statistically significant differences in birth weight (p=0.043), intrauterine growth restriction (IUGR) (p=0.028), Apgar score at 1 min Izolirana hipotiroksinemija majke (IMH) je prisutnost niske koncentracije ukupnog tiroksina (TT4) u majke u kombinaciji s normalnim majčinim hormonom za stimulaciju štitnjače (TSH). Cilj naše studije bio je istražiti je li IMH povezan sa štetnim ishodom trudnoće u Sjevernoj Makedoniji. U 359 trudnica koje su zadovoljile kriterije uzeti su uzorci osušene kapi krvi koji su analizirani na TT4 i TSH. Podaci nakon porođaja uneseni su za svaku majku iz njihove povijesti bolesti. Od ukupno 359 žena 131 (37,42%) je pripadala skupini IMH. Utvrđene su statistički značajne razlike u porođajnoj težini (p=0,043), intrauterinom ograničenju rasta (IUGR) (p=0,028), Apgar zbroju u 1. minuti |
| Databáze: | OpenAIRE |
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