An Update of Lectins from Marine Organisms: Characterization, Extraction Methodology, and Potential Biofunctional Applications
| Autor: | Ahmmed, M. K., Bhowmik, S., Giteru, S. G., Zilani, M. N. H., Adadi, P., Islam, S. S., Kanwugu, O. N., Haq, M., Ahmmed, F., Ng, C. C. W., Chan, Y. S., Asadujjaman, M., Chan, G. H. H., Naude, R., Bekhit, A. E. -D. A., Ng, T. B., Wong, J. H. |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: |
HOMEOSTASIS
ZEBRA FISH ANTIINFECTIVE AGENT MUCUS LACTOSE BINDING LECTIN DERIVATIVE HEMAGGLUTININ ANTINEOPLASTIC AGENT ANTIBACTERIAL ACTIVITY PENAEUS JAPONICUS MANNOSE UNCLASSIFIED DRUG PLANT LECTIN GALACTOSE AFFINITY CHROMATOGRAPHY ADHESINS XYLOSE CARP RED ALGA IMMUNOLOGIC AGENT ANTIVIRUS AGENT MALIGNANT NEOPLASM PHYSIOLOGICAL PROCESS INTESTINE FLORA CD209 ANTIGEN MYTILECTIN DERIVATIVE GLYCOPROTEIN IMMUNOMODULATION HUMAN RHAMNOSE BINDING LECTIN CLS3 ANTIVIRAL ACTIVITY AQUATIC ORGANISMS ANTIFUNGAL AGENT FUCOLECTIN CRUSTACEA BIVALVE FISHES C TYPE LECTIN DERIVATIVE GLUCAN MANNAN DRUG ISOLATION GALAPTIN DRUG PURIFICATION GALECTIN MUSCLE TISSUE MYTILUS CALIFORNIANUS EXTRACTION AND PURIFICATION STRIPED BASS ADHESIN AQUATIC SPECIES PLANT LECTINS CRYSTAL STRUCTURE HEMAGGLUTININS FISH NONHUMAN REVIEW IMMUNOSTIMULATING AGENT LECTINS C-TYPE DRUG STRUCTURE MARINE LECTINS FOOD SAFETY SEA URCHIN CORONAVIRINAE RHAMNOSE GALECTIN 1 L2 MANNOSE BINDING LECTIN ANIMALS ANIMAL LECTIN ANTINEOPLASTIC ACTIVITY GALECTINS PEPTIDOGLYCAN SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 MARINE SPECIES GLYCOPROTEINS MYTILUS FUCOSE BINDING LECTIN DERIVATIVE ONCORHYNCHUS KETA BIOLOGICAL ACTIVITY BIO-FUNCTIONAL ROLES CHARACTERIZATION GALECTIN 3 1 3 GLUCAN GALECTIN 4 |
| Zdroj: | Marine Drugs |
| Popis: | Lectins are a unique group of nonimmune carbohydrate-binding proteins or glycopro-teins that exhibit specific and reversible carbohydrate-binding activity in a non-catalytic manner. Lectins have diverse sources and are classified according to their origins, such as plant lectins, animal lectins, and fish lectins. Marine organisms including fish, crustaceans, and mollusks produce a myriad of lectins, including rhamnose binding lectins (RBL), fucose-binding lectins (FTL), mannose-binding lectin, galectins, galactose binding lectins, and C-type lectins. The widely used method of extracting lectins from marine samples is a simple two-step process employing a polar salt solution and purification by column chromatography. Lectins exert several immunomodulatory functions, including pathogen recognition, inflammatory reactions, participating in various hemocyte functions (e.g., agglutination), phagocytic reactions, among others. Lectins can also control cell prolifer-ation, protein folding, RNA splicing, and trafficking of molecules. Due to their reported biological and pharmaceutical activities, lectins have attracted the attention of scientists and industries (i.e., food, biomedical, and pharmaceutical industries). Therefore, this review aims to update current information on lectins from marine organisms, their characterization, extraction, and biofunctionali-ties. © 2022 by the authors. Licensee MDPI, Basel, Switzerland. Ural Federal University, UrFU The author O.N.K is grateful to the “Priority 2030” program of the Ural Federal University for support. |
| Databáze: | OpenAIRE |
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