| Autor: |
Munster, Pamela, Bergsland, Emily, Kelley, Robin Kate, Bendell, JC, Kelley, RK, Shih, KC, Grabowsky, JA, Jones, S, Martin, T, Infante, JR, Mischel, PS, Matsutani, T |
| Jazyk: |
angličtina |
| Rok vydání: |
2015 |
| Zdroj: |
Munster, Pamela; Bergsland, Emily; Kelley, Robin Kate; Bendell, JC; Kelley, RK; Shih, KC; et al.(2015). A phase i dose-escalation study to assess safety, tolerability, pharmacokinetics, and preliminary efficacy of the dual mTORC1/mTORC2 kinase inhibitor CC-223 in patients with advanced solid tumors or multiple myeloma. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/9sq7h6jn |
| Popis: |
© 2015 American Cancer Society.BACKGROUND The mammalian target of rapamycin (mTOR) pathway is essential for tumor development, yet mTOR inhibitors have yielded modest results. This phase 1 study investigated the mTORC1/mTORC2 inhibitor CC-223 in patients w |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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