Accurate measurement of blood vessel depth in port wine stained human skin in vivo using pulsed photothermal radiometry
| Autor: | Li, B, Majaron, B, Viator, JA, Milner, TE, Chen, Z, Zhao, Y, Ren, H, Nelson, JS |
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| Jazyk: | angličtina |
| Rok vydání: | 2004 |
| Předmět: |
congenital
hereditary and neonatal diseases and abnormalities Spectrophotometry Infrared Light Port-Wine Stain Biomedical Engineering Optical Physics Sensitivity and Specificity Image Interpretation Computer-Assisted Humans Tomography Optical Radiometry two-wavelength excitation Ophthalmology And Optometry Skin nutritional and metabolic diseases Reproducibility of Results Optics Image Enhancement nervous system diseases Thermography pulsed photothermal radiometry photothermal profiling Blood Vessels port wine stain optical Doppler tomography Algorithms |
| Zdroj: | Li, B; Majaron, B; Viator, JA; Milner, TE; Chen, Z; Zhao, Y; et al.(2004). Accurate measurement of blood vessel depth in port wine stained human skin in vivo using pulsed photothermal radiometry. Journal of Biomedical Optics, 9(5), 961-966. doi: 10.1117/1.1784470. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/0z09h16m |
| Popis: | We report on application of pulsed photothermal radiometry (PPTR) to determine the depth of port wine stain (PWS) blood vessels in human skin. When blood vessels are deep in the PWS skin (>100 μm), conventional PPTR depth profiling can be used to determine PWS depth with sufficient accuracy. When blood vessels are close or partially overlap the epidermal melanin layer, a modified PPTR technique using two-wavelength (585 and 600 nm) excitation is a superior method to determine PWS depth. A direct difference approach in which PWS depth is determined from a weighted difference of temperature profiles reconstructed independently from two-wavelength excitation is demonstrated to be appropriate for a wider range of PWS patients with various blood volume fractions, blood vessel sizes, and depth distribution. The most superficial PWS depths determined in vivo by PPTR are in good agreement with those measured using optical Doppler tomography (ODT). © 2004 Society of Photo-Optical Instrumentation Engineers. |
| Databáze: | OpenAIRE |
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