Isolation of two cytotoxic diterpenes from the fern Pteris multifida

Autor: Woerdenbag, HJ, Lutke, LR, Bos, R, Stevens, JF, Hulst, R, Kruizinga, WH, Elema, ET, Hendriks, H, vanUden, W, Pras, N
Přispěvatelé: Molecular Inorganic Chemistry, University of Groningen
Jazyk: angličtina
Rok vydání: 1996
Předmět:
Zdroj: Zeitschrift fur naturforschung c-A journal of biosciences, 51(9-10), 635-638
ISSN: 0939-5075
Popis: From aerial parts of the fern Pteris multifida Poir. (Polypodiaceae) two diterpenes, ent-kaurane-2 beta,16 alpha-diol and ent-kaur-16-ene-2 beta,15 alpha-diol, were isolated by repeated column chromatography using silica gel and silica gel impregnated with silver nitrate. The structures were confirmed by spectroscopic methods. Both compounds showed a moderate cytotoxicity to Ehrlich ascites tumour cells.
Databáze: OpenAIRE