Autor: |
Raasveld, M. H., Bloemena, E., Surachno, S., ten Berge, R. J. |
Přispěvatelé: |
Other departments |
Jazyk: |
angličtina |
Rok vydání: |
1992 |
Předmět: |
|
Zdroj: |
Nephrology, dialysis, transplantation, 7(6), 530-533. Oxford University Press |
ISSN: |
0931-0509 |
Popis: |
T gamma/delta lymphocytes are able to perform allospecific cytotoxicity and natural killer cytotoxicity in vitro. However, very little is known about their function in vivo. To investigate the possible involvement of T gamma/delta lymphocytes in the immune response to renal allografts, fine-needle aspiration biopsies and peripheral blood of 15 renal transplant recipients were studied during the first 4 weeks after transplantation. In addition peripheral blood of patients before transplantation, half a year and one year after transplantation was studied. No increase in the percentage of T gamma/delta lymphocytes in the fine-needle aspiration biopsies, including those taken during acute rejection episodes, was found. A significant decrease in the percentage of T gamma/delta lymphocytes was observed in peripheral blood after transplantation. We conclude that T gamma/delta lymphocytes seem to play no major role in the immune response to renal allografts |
Databáze: |
OpenAIRE |
Externí odkaz: |
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