Twenty-four-hour non-invasive monitoring of systemic haemodynamics and cerebral blood flow velocity in healthy humans

Autor: Diamant, M., Harms, M. P. M., Immink, R. V., van Lieshout, J. J., van Montfrans, G. A.
Přispěvatelé: Anesthesiology, Medical Biology, General Internal Medicine, Vascular Medicine
Jazyk: angličtina
Rok vydání: 2002
Zdroj: Acta physiologica Scandinavica, 175(1), 1-9. Wiley-Blackwell
ISSN: 0001-6772
Popis: Acute short-term changes in blood pressure (BP) and cardiac output (CO) affect cerebral blood flow (CBF) in healthy subjects. As yet, however, we do not know how spontaneous fluctuations in BP and CO influence cerebral circulation throughout 24 h, We performed simultaneous monitoring of BP, systemic haemodynamic parameters and blood flow velocity in the middle cerebral artery (MCAV) in seven healthy subjects during a 24-h period, Finger BP was recorded continuously during 24 h by Portapres and bilateral MCAV was measured by transcranial Doppler (TCD) during the first 15 min of every hour. The subjects remained supine during TCD recordings and during the night, otherwise they were seated upright in bed. Stroke volume (SV), CC and total peripheral resistance (TPR) were determined by Modelflow analysis. The 15 min mean value of each parameter was assumed to represent the mean of the corresponding hour. There were no significant differences between right vs. left, nor between mean daytime vs. night time MCAV. Intrasubject comparison of the twenty-four 15-min MCAV recordings showed marked variations (P
Databáze: OpenAIRE
Externí odkaz: