Long-term outcome and quality of life after arterial switch operation: a prospective study with a historical comparison

Autor: Ruys, Titia P. E., van der Bosch, Annemien E., Cuypers, Judith A. A. E., Witsenburg, Maarten, Helbing, Willem A., Bogers, Ad J. J. C., van Domburg, Ron, McGhie, Jacky S., Geleijnse, Marcel L., Henrichs, Jens, Utens, Elisabeth, van der Zwaan, Heleen B., Takkenberg, Johanna J. M., Roos-Hesselink, Jolien W.
Přispěvatelé: Academic Medical Center
Jazyk: angličtina
Rok vydání: 2013
Zdroj: Congenital heart disease, 8(3), 203-210. Wiley-Blackwell
ISSN: 1747-079X
Popis: AIM.: The study aims to describe the long-term cardiological and psychological results of our first surgical cohort of arterial switch operation (ASO) patients and compare the results with our earlier series of Mustard patients. METHODS.: Twenty-four survivors of ASO operated in our center (1985-1990) were evaluated by electrocardiography, echocardiography, magnetic resonance imaging, exercise testing, 24-hour Holter-monitoring, and health-related quality of life questionnaire. The results were compared with 58 adult Mustard patients who were evaluated in 2001 using the same study protocol. RESULTS.: Arterial switch operation was performed at a median age of 13 days and Mustard operation at 2 years. Median follow-up was 22 years (range 20-25) and 25 years (22-29), respectively. After ASO, survival was better (P =.04). The event-free survival after 22 years was 77% after ASO vs. 44% after Mustard (P =.03). Good systemic ventricular function was present in 93% after ASO vs. 6% after Mustard (P
Databáze: OpenAIRE