Coma and haemodynamic instability in the context of trauma

Autor: Gietler, A., Pragt, E., Sels, J. W. E. M., Hannemann, P. F. W., Bouman, E. A., Bergmans, D. C. J. J., van Mook, W. N. K. A.
Přispěvatelé: MUMC+: MA Arts Assistenten IC (9), Intensive Care, MUMC+: MA Medische Staf IC (9), MUMC+: MA Anesthesiologie (9), MUMC+: MA Med Staf Spec Cardiologie (9), RS: NUTRIM - R3 - Respiratory & Age-related Health, MUMC+: MA Heelkunde (9), RS: NUTRIM - R2 - Gut-liver homeostasis
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Netherlands Journal of Critical Care, 25(6), 210-214. Netherlands Society for Intensive Care,Nederlandse Vereniging voor Intensive Care
ISSN: 1569-3511
Popis: Coma and haemodynamic instability in a trauma patient due to propranolol intoxication. A 51-year-old female was involved in a car accident. Following this event she first became comatose followed by haemodynamic instability (hypotension and later bradycardia). Eventually it proved that these were attributable to a beta-blocker intoxication (propranolol) and not to the trauma. In case of propranolol intoxication (which is highly lipophilic) coma can precede the haemodynamic symptoms. Furthermore, hypotension can precede bradycardia because the negative inotropic effects occur earlier than the negative chronotropic effects.
Databáze: OpenAIRE