Expression and localization of renin and angiotensinogen in rat heart after myocardial infarction

Autor: Passier, R. C., Smits, J. F., Verluyten, M. J., Daemen, M. J.
Přispěvatelé: Other departments
Jazyk: angličtina
Rok vydání: 1996
Předmět:
Zdroj: American journal of physiology, 271(3 Part 2), H1040-H1048. American Physiological Society
ISSN: 0002-9513
Popis: Wistar-Kyoto rats underwent myocardial infarction (MI) or sham surgery. At different time points after surgery (1-90 days), hearts were removed and divided into infarcted left ventricle (LV), noninfarcted septum, and right ventricle. The tissues were used for total RNA isolation or Formalin fixation for in situ hybridization (ISH). Renin and angiotensinogen mRNA contents were quantified by the competitive reverse transcriptase polymerase chain reaction. We found a 4-, 14-, and 8-fold increase (P
Databáze: OpenAIRE