EFFECTS OF 22 MONTHS OF TREATMENT WITH INHALED CORTICOSTEROIDS AND OR BETA-2-AGONISTS ON LUNG-FUNCTION, AIRWAY RESPONSIVENESS, AND SYMPTOMS IN CHILDREN WITH ASTHMA

Autor: VANESSENZANDVLIET, EE, HUGHES, MD, WAALKENS, HJ, DUIVERMAN, EJ, POCOCK, SJ, KERREBIJN, KF
Přispěvatelé: Faculteit Medische Wetenschappen/UMCG
Jazyk: angličtina
Rok vydání: 1992
Předmět:
Zdroj: American Review of Respiratory Disease, 146(3), 547-554
ISSN: 0003-0805
Popis: In a randomized double-blind multicenter clinical study, 116 children with asthma were randomly assigned to treatment with an inhaled beta-2-agonist (salbutamol 0.2 mg) plus an inhaled corticosteroid (budesonide 0.2 mg) three times a day (BA + CS) or to an inhaled beta-2-agonist (salbutamol 0.2 mg) plus a placebo three times a day (BA + PL). After a median follow-up time of 22 months, 26 patients receiving BA + PL (45%) had withdrawn from randomized treatment, mainly because of asthma symptoms, compared with three withdrawals in the patients receiving BA + CS (p
Databáze: OpenAIRE