Changes in Superior Mesenteric Blood Flow Produced by Splanchnic Nerve and Hypovolemic Stimulation in Rats

Autor: Fujita, Nobuhiro, Aono, Takashi, Sakaguchi, Takeo, Ohtake, Masahiro, Tsukada, Kazuhiro, Hatakeyama, Katsuyoshi
Jazyk: angličtina
Rok vydání: 1996
Předmět:
Zdroj: Acta medica et biologica. 44(2):87-91
ISSN: 0567-7734
Popis: Changes in superior mesenteric venous blood flow (SMVF) were examined in rats following splanchnic nerve and hypovolemic stimulation. The splanchnic nerve branch to the liver was sectioned in all rats tested. SMVF was decreased after electrical stimulation of the left splanchnic nerve, and SMVF was reduced in parallel with the volume of blood withdrawn (1.0, 2.0 and 2.5 ml per body). The SMVF response after nerve stimulation was decreased according to the volume of blood withdrawn. Noradrenaline injected into the superior mesenteric vein reduced SMVF in a dose-dependent fashion. Splanchnic nerve stimulation decreased superior mesenteric arterial blood flow (SMAF), but the reduction in SMAF was similar for all three degrees of hypovolemia. These results suggest that the sympathetic nerve directly moderates blood flow in the superior mesenteric vein through adrenergic fibers. With blood loss, sympathetic mesenteric control of the venous but not the arterial circulation is moderated.
Databáze: OpenAIRE