Positron Emission Tomography (PET) for oncologic applications in oral region

Autor: Masanori, SHOZUSHIMA, Kazunori, TERASAKI
Přispěvatelé: 総説, Review, 岩手医科大学歯学部 歯科放射線学講座, 岩手医科大学サイクロトロンセンター, Department of Dental Radiology, School of Dentistry, Iwate Medical University, Cyclotron Research Center, Iwate Medical University
Jazyk: japonština
Rok vydání: 2004
Předmět:
Zdroj: 岩手医科大学歯学雑誌 = Dental journal of Iwate Medical University. 29(3):213-223
Popis: A rapidly emerging clinical application of positron emission tomography (PET) is the detection of cancer with radionuchde tracer, because it provides information unavailable by ultrasound, computed tomography or magnetic resonance imaging The most commonly used radiotracer for PET oncologic imaging is fluorme-18-labeled fluorodeoxyglucose (^F-FDG) Early studies show PET has potential value in viewing the region of the tumor, detecting, staging, grading, monitoring response to anticancer therapy, and differentiating recurrent or residual disease from post treatment changes. However, limitations of FDG-PET in the head and neck region, namely, physiological FDG uptake in the salivary glands and palatine tonsils, have been reported, increasing the false-positive rates in image interpretation. This review was designed to address these distinctions of oral cancer PET imaging (1) Specialization of PET equipment, (2) Cancer cell metabolism, proliferation and tracers, (3) Clinical diagnosis of oral cancer with PET, (4) Pitfalls in oncologic diagnosis with FDG-PET imaging.
Databáze: OpenAIRE