Comparison between endoscopic findings and FDG-PET/CT that shows diffuse gastric uptakes in cancer screening

Autor: Tamura, Katsumi, Sakata, Ikuko, Ishida, Jiro, Machida, Kikuo, Yoshikawa, Kyosan, Hasebe, Mitsuhiko, Toubaru, Sachiko, Ohashi, Seiya, Kosuda, Shigeru, Abe, Yoshiyuki
Jazyk: angličtina
Rok vydání: 2009
Popis: Purpose: FDG uptakes in the stomach, especially diffuse uptakes often pester nuclear medicine physicians with the interpretation as to whether The purpose of this study is to investigate the necessity of endoscopy after FDG-PET/CT that shows diffuse gastric uptakes in cancer screening. Materials and methods: We studied 50 people who had a check-up for cancer using FDG-PET/CT. All people showed diffuse uptakes in the stomach. Fifteen people were female and thirty-five people were male, and mean age was 57.3pm10.1 (36 to 80). The uptakes of the stomach were higher than of the liver in 32 people, similar to the liver in 12 people, and lower than of the liver in 6 people. Thirty-two people underwent biopsy from the stomach. Pathological findings were categorized into five groups according to the following scale: Group 1: normal tissue or benign lesion without atypical cell; Group 2: benign lesion with atypical cell ; Group 3: borderline lesion; Group 4: suspicion of cancer; Group5: cancer. Results: All people had no gastric cancer. Gastritis was detected in 35 people, ulcer in 2 people, hyperplastic polyp in 2 people, metaplasia in one. Ten people had normal findings. On the value of SUV, there was no significant difference between gastritis (3.65pm0.60SD) and normal findings (3.55pm0.33SD, p=0.619). The specimens from biopsy were Group 1 in 27 people and Group 2 in 8 people. No specimens showed Group 3, Group4, and Group 5. No significant difference was found between Group 1 (3.55pm0.59SD) and Group 2 (3.68pm0.60SD). Helicobacter.pylori was detected in 17 people. No significant difference was found between H.pylori positive group (3.70pm0.46SD) and negative group (3.43pm0.71SD, p=0.198). Conclusion: Our results indicate that an additional endoscopy for detecting gastric cancer does not seem to be necessary after FDG-PET/CT that shows diffuse uptakes in the stomach.
The 2009 EANM Congress
Databáze: OpenAIRE
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