| Autor: |
Ura, Sawako, Miyata, Manabu, Ooto, Sotaro, Yasuhara, Satoshi, Tamura, Hiroshi, Ueda-Arakawa, Naoko, Muraoka, Yuki, Miyake, Masahiro, Takahashi, Ayako, Wakazono, Tomotaka, Uji, Akihito, Yamashiro, Kenji, Tsujikawa, Akitaka |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Retina : The Journal of Retinal and Vitreous Diseases. 42(4):661-668 |
| ISSN: |
0275-004X |
| Popis: |
[Purpose:] To investigate predictors of early displacement of submacular hemorrhage (SMH) by simple intravitreal SF₆ gas injection. [Methods:] This retrospective study included 16 eyes of 16 consecutive patients (age: 74.5 ± 7.7 years; 15 men) with large SMH treated with simple intravitreal SF₆ gas before inception of subretinal tissue plasminogen activator (tPA) injection at our institution. We graded SMH displacement at 1-week posttreatment as 0, 1, or 2. Central retinal thickness, central choroidal thickness, SMH height, SMH area, disease duration, use of anticoagulant or antiplatelet drugs, and contrast-to-noise ratio (CNR) of SMH on optical coherence tomography (OCT) images were recorded. Correlations between displacement grading and baseline parameter were analyzed. [Results:] Univariable correlation analysis revealed association of the 1-week displacement grading with the CNR (P = 0.004, r = −0.68) and SMH height (P = 0.03, r = −0.55). The CNR was most strongly associated with 1-week displacement on multivariable correlation analysis (P = 0.01, β = −0.60). [Conclusions:] Our findings showed that the CNR of SMH was a useful predictor of early displacement of large SMH after simple intravitreal SF₆ gas injection. When vitrectomy with subretinal injection of tPA is difficult in patients with large SMH, with low CNR on OCT, simple intravitreal SF₆ gas injection may be a treatment option. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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