Retrospective Study of Colposcopy for Precancerous Cervical Lesions and Correlation between Diagnosis and Number of Biopsy Specimens
| Autor: | Takahashi, Rena, Kubushiro, Kaneyuki, Murakami, Isao, Kugimiya, Tsuyoki, Tanaka, Kyoko, Morita, Mineto |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: | |
| Zdroj: | Toho Journal of Medicine. 6(3):99-103 |
| ISSN: | 2189-1990 |
| Popis: | Original Article Introduction: Histological diagnosis is performed in patients with abnormal findings on cervical cytology and macroscopic abnormalities of the cervix. In general, targeted histological diagnosis is performed to extract the specimens from lesions with abnormal findings under a colposcope. In this study, we aim to retrospectively verify the number of specimens from different cervical lesions that are most effective for diagnosis. Methods: We included women with abnormal findings on cervical cytology who underwent targeted biopsy under a colposcope in our hospital from August 2013 to March 2016. The number of specimens extracted and the number of biopsies required to achieve diagnosis were examined in patients with cervical histopathology showing cervical intraepithelial neoplasia (CIN)1, CIN2, and CIN3. Furthermore, when cervical histology showed indications for conization and total hysterectomy, these procedures were performed to confirm the ultimate histopathological diagnosis. Results: The definite diagnosis of CIN was made from one, one and two, and one, two, and three biopsies in 81.6%, 96.1%, and 100% patients, respectively. Conclusions: All patients with CIN1 to CIN3 were diagnosed with three biopsies. In particular, higher number of biopsies was associated with higher rates of definite diagnosis. However, in no cases, definite CIN diagnosis was made at the four biopsies, suggesting that four or more cervical histological biopsies are generally unnecessary. Furthermore, given that 100% patients were diagnosed by their three biopsies, and at most, only three biopsies should be performed. |
| Databáze: | OpenAIRE |
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