Physical Activity and Renal Function Declines in Patients with Chronic Kidney Disease

Autor: Nambu, Michiharu, Kohagura, Kentaro, Ishida, Akio, Sakima, Atsushi, Yamazato, Masanobu, Ohya, Yusuke
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: 琉球医学会誌 = Ryukyu Medical Journal. 40(1-4):9-15
ISSN: 1346-888X
Popis: Objectives: Physical activity was suggested to decline as the stage of chronic kidney disease (CKD) advances. This study aimed to examine the impact of physical activity on developing CKD independent of comorbidity. Methods: Among 305 CKD patients (stages 3–5) who had been treated at the outpatient care of our department at the University of the Ryukyus Hospital and who participated in the physical activity survey, 208 were finally enrolled in this study after applying the exclusion criteria. The patients' amounts of physical activity were assessed using the International Physical Activity Questionnaire Short Version. The changes in estimated glomerular filtration rate (eGFR) were retrospectively examined according to the quartile of baseline physical activity time for 36 months. Results: The physical activity times were 25.7, 21.4, and 12.2 min/day in stages 3, 4, and 5, respectively. Diabetes mellitus and lower hemoglobin level were significantly associated with lower physical activity. Patients with the lowest quartile of physical activity showed greater decline in eGFR. Multivariate regression analysis revealed that the lowest quartile of physical activity was significantly associated with greater decline in eGFR independent of confounding factors. Conclusions: Lower physical activity might be independently associated with greater decline in renal function among CKD patients.
Databáze: OpenAIRE