Dyslipidemia after Kidney Transplantation; A Study at Hirosaki University Hospital
| Autor: | Fujita, Takeshi, Narita, Ikuyo, Shimada, Michiko, Nakamura, Norio, Osawa, Hiroshi, Yamabe, Hideaki, Okumura, Ken, Murakami, Reiichi, Narumi, Shunji, Ohyama, Chikara |
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| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: | |
| Zdroj: | 弘前医学. 64:S134-S137 |
| ISSN: | 0439-1721 |
| Popis: | Although graft survival rates in kidney transplant recipients have improved over the years. Cardiovascular disease remains the major cause of death after kidney transplantation. Therefore, relevant control of dyslipidemia is important for both the prevention of cardiovascular disease and protection of graft function. We retrospectively analyzed 28 patients who underwent kidney transplantation from June 2006 to February 2011 at Hirosaki University Hospital, of which 6 were excluded because of insufficient data. We applied the following diagnostic criteria for dyslipidemia established by the Japan Atherosclerosis Society: （1） low-density lipoprotein cholesterol levels ≥ 140 mg/dl, （2） triglyceride levels ≥ 150 mg/dl, and （3） high-density lipoprotein cholesterol levels < 40 mg/dl. Serum samples were obtained after overnight fasting. Five patients had dyslipidemia before kidney transplantation, and 4 patients developed new-onset dyslipidemia after kidney transplantation. Although 13 patients had normal lipid levels, 5 of them received prophylactic medication for dyslipidemia. We analyzed the 3 groups of patients to determine risk factors for dyslipidemia related kidney transplantation. Our data suggested that high trough levels of tacrolimus （Tac） tended to correlate with new-onset dyslipidemia after kidney transplantation（ P=0.06）. 弘前医学. 64(Suppl.), 2013, p.S134-S137 |
| Databáze: | OpenAIRE |
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