Atypical Hemolytic Uremic Syndrome following Acute Type A Aortic Dissection

Autor:	Ikushima, Eigo, Hisahara, Manabu, Nishijima, Takuya, Uchiyama, Hikaru, Onzuka, Tatsushi, Ochiai, Yoshie, Muta, Tsuyoshi, Tokunaga, Shigehiko
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	Article Subject hemic and lymphatic diseases urologic and male genital diseases
Zdroj:	Case Reports in Hematology.
ISSN:	2090-6560
DOI:	10.1155/2020/2467953
Popis:	Atypical hemolytic uremic syndrome (aHUS) is a thrombotic microangiopathy (TMA)-related disease that manifests as a triad of microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury (AKI) and is caused by uncontrolled activation of the complement system. We report the case of a 61-year-old woman with acute type A aortic dissection that subsequently developed into aHUS. The hematologic disorders underlying aHUS improved after treatment with the complement inhibitor eculizumab. It is important to consider aHUS when a patient clinically develops a triad of microangiopathic hemolytic anemia, thrombocytopenia, and an increasing creatinine level following cardiovascular surgery.
Databáze:	OpenAIRE
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