| Autor: |
Kaparou, Maria, Rudzki, Zbigniew, Giles, Hannah, Murthy, Vidhya, Srinath, Swathy, Lloyd, Rebecca, Ahmed, Maria Zahid, Salhan, Beena, Chauhan, Saleena, Kishore, Bhuvan, Lovell, Richard, Horgan, Claire, Paneesha, Shankara, Xenou, Evgenia, Lokare, Anand, Ewing, Joanne, Dassanayake, Hansini, Nikolousis, Emmanouil, Kanellopoulos, Alexandros |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
Case Reports in Hematology. |
| ISSN: |
2090-6560 |
| DOI: |
10.1155/2021/8843063 |
| Popis: |
The present study describes a patient aged 70 with very high-risk AML who successfully received a nonmyeloablative matched unrelated donor allograft shortly following SARS-CoV-2 infection, which manifested with mild cough, interstitial abnormalities on chest CT, and pancytopenia with profound bone marrow biopsy histological alterations. In parallel, our study provides bone marrow biopsy data in a series of contemporary patients with serious haematological diseases who had a bone marrow biopsy performed within two weeks of PCR confirmation of SARS-CoV-2 infection. This study is notable because there are no published data describing the bone marrow biopsy changes observed in patients with haematological malignancies and SARS-CoV-2 infection. Finally, it is suggested that nonmyeloablative hematopoietic stem cell transplantation for very high-risk haematological malignancies can be successfully performed following recovery from SARS-CoV-2 infection. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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