Development of a system based on artificial intelligence to identify visual problems in children: study protocol of the TrackAI project
| Autor: | Pinilla J, Pueyo, Irene Altemir, T. Perez-Roche, Jose Echevarria, E. Prieto, Adrian Alejandre, Romero-Sanz M, A. Fanlo-Zarazaga, Marta Ortin, O. Castillo, Cipres M, Pan X, Diego Gutierrez, Inmaculada González, Belen Masia |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Asia
Adolescent genetic structures Cost-Benefit Analysis Visual impairment Vision Disorders visual impairment Amblyopia 03 medical and health sciences 0302 clinical medicine Vision Screening Protocol Medicine Humans Multicenter Studies as Topic 030212 general & internal medicine Trial registration Child childhood Protocol (science) Digital device System development Clinical Trials as Topic business.industry Visual test Infant General Medicine artificial intelligence United States Europe Ophthalmology Clinical research ethics Child Preschool Good clinical practice Artificial intelligence Smartphone medicine.symptom business 030217 neurology & neurosurgery |
| Zdroj: | Zaguán. Repositorio Digital de la Universidad de Zaragoza Consejo Superior de Investigaciones Científicas (CSIC) BMJ Open |
| Popis: | IntroductionAround 70% to 80% of the 19 million visually disabled children in the world are due to a preventable or curable disease, if detected early enough. Vision screening in childhood is an evidence-based and cost-effective way to detect visual disorders. However, current screening programmes face several limitations: training required to perform them efficiently, lack of accurate screening tools and poor collaboration from young children.Some of these limitations can be overcome by new digital tools. Implementing a system based on artificial intelligence systems avoid the challenge of interpreting visual outcomes.The objective of the TrackAI Project is to develop a system to identify children with visual disorders. The system will have two main components: a novel visual test implemented in a digital device, DIVE (Device for an Integral Visual Examination); and artificial intelligence algorithms that will run on a smartphone to analyse automatically the visual data gathered by DIVE.Methods and analysisThis is a multicentre study, with at least five centres located in five geographically diverse study sites participating in the recruitment, covering Europe, USA and Asia.The study will include children aged between 6 months and 14 years, both with normal or abnormal visual development.The project will be divided in two consecutive phases: design and training of an artificial intelligence (AI) algorithm to identify visual problems, and system development and validation. The study protocol will consist of a comprehensive ophthalmological examination, performed by an experienced paediatric ophthalmologist, and an exam of the visual function using a DIVE.For the first part of the study, diagnostic labels will be given to each DIVE exam to train the neural network. For the validation, diagnosis provided by ophthalmologists will be compared with AI system outcomes.Ethics and disseminationThe study will be conducted in accordance with the principles of Good Clinical Practice. This protocol was approved by the Clinical Research Ethics Committee of Aragón, CEICA, on January 2019 (Code PI18/346).Results will be published in peer-reviewed journals and disseminated in scientific meetings.Trial registration numberNCT17316993. |
| Databáze: | OpenAIRE |
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