A glycoprotein in the accessory cell of the echinoid ovary and its role in vitellogenesis
| Autor: | Osamu Moriya, Hironobu Ozaki, Frederick Elton Harrington |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
chemistry.chemical_classification
Glycan food.ingredient biology Ovary Oocyte biology.organism_classification Strongylocentrotus purpuratus Cell biology medicine.anatomical_structure food chemistry Yolk embryonic structures Immunology Genetics medicine biology.protein Vitellogenesis Antigen-presenting cell Glycoprotein Developmental Biology |
| Zdroj: | Roux's archives of developmental biology : the official organ of the EDBO. 195(1) |
| ISSN: | 0930-035X |
| Popis: | A high-molecular-weight glycoprotein with a sedimentation coefficient of 22.6 has been isolated and characterized from the accessory cells in the previtellogenic ovary of the echinoid Dendraster excentricus. This glycoprotein is similar to the major yolk glycoprotein of the mature egg in its electrophoretic mobility under non-denaturing conditions, high mannose-type glycan, amino acid composition, constitutive glycopeptides, and immunological determinants. Previous histological and electron microscopical analyses led to the hypothesis that vitellogenesis involves a translocation of material from the accessory cell in the ovary to the oocyte. Because of the close similarities of the accessory cell glycoprotein to the yolk glycoprotein of the mature egg, we conclude that the glycoprotein in the accessory cell is a precursor to the major glycoprotein of the egg yolk. This conclusion is further supported by our additional finding that the accessory cell of another echinoid, Strongylocentrotus purpuratus, also contains a high-molecular-weight (24 S) glycoprotein which shows similarities to the yolk glycoprotein of the mature egg in the carbohydrate moiety and the constitutive glycopeptides. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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