Blue Light-Mediated, Photocatalyst-Free Decarboxylative Alkylation of Heteroaryl Sulfinimines

Autor:	Zhe Zhou, Zachary S. Sales, Daniel J. Pippel, Michael Qian, Connor L. Martin
Rok vydání:	2022
Předmět:	Molecular Structure Alkylation Organic Chemistry Imines Catalysis
Zdroj:	The Journal of organic chemistry. 87(21)
ISSN:	1520-6904
Popis:	We report a diastereoselective, photocatalyst-free decarboxylative alkylation of (hetero)aryl sulfinimines using redox-active esters under blue light. High yields and diastereoselectivities can be achieved under mild conditions, and we demonstrate its utility as a synthetic method, especially for medicinal chemists.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffb258e89c1478d7e2862f57e8a8c9e8 https://pubmed.ncbi.nlm.nih.gov/36228170 Zobrazit plný text záznamu