Relation between unconjugated bilirubin and RDW, neutrophil to lymphocyte ratio, platelet to lymphocyte ratio in Gilbert’s syndrome
| Autor: | Erol Arslan, Mustafa Tanriseven, Mustafa Cakar, Hakan Sarlak, Fatih Bulucu, Muharrem Akhan, Salim Ozenc |
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| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
Lymphocyte Red cell distribution width Gilbert’s syndrome Negative association 030204 cardiovascular system & hematology Coronary artery disease 03 medical and health sciences 0302 clinical medicine Internal medicine Medicine Platelet Neutrophil to lymphocyte ratio Multidisciplinary Platelet to lymphocyte ratio business.industry Research Red blood cell distribution width medicine.disease Gilbert's syndrome Unconjugated bilirubin medicine.anatomical_structure Endocrinology 030220 oncology & carcinogenesis business |
| Zdroj: | SpringerPlus |
| ISSN: | 2193-1801 |
| DOI: | 10.1186/s40064-016-3085-5 |
| Popis: | Background Unconjugated bilirubin (UCB) plays a protective role in coronary artery disease. Red cell distribution width (RDW), neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) are inflammatory biomarkers and higher levels are related to atherosclerosis and adverse cardiovascular events. Aim We aimed to investigate the relation between UCB levels and RDW, NLR, PLR in people with Gilbert’s syndrome (GS). Materials and methods We selected 2166 subjects (1082 with GS and 1084 healthy controls) from a database having 33,695 people. RDW, NLR and PLR were investigated in the subjects with GS and compared with the healthy controls. Linear regression analysis was used to evaluate the relation between variables. Results NLR and PLR were higher in the subjects with GS compared to the controls (p |
| Databáze: | OpenAIRE |
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