Successful treatment of vulvovaginal lichen planus with tildrakizumab: A case series of 24 patients

Autor:	Ashod Kherlopian, Gayle Fischer
Rok vydání:	2022
Předmět:	Chronic Disease Lichen Planus Quality of Life Humans Female Dermatology Antibodies Monoclonal Humanized
Zdroj:	Australasian Journal of Dermatology. 63:251-255
ISSN:	1440-0960 0004-8380
DOI:	10.1111/ajd.13793
Popis:	Vulvovaginal lichen planus (VLP) is a chronic inflammatory dermatosis affecting the genital skin and mucosa that can have a profound negative impact on patient quality of life. Up to 43% of women with VLP require systemic immunosuppression to achieve disease remission, and some individuals prove to be highly treatment resistant. We present a case series of 24 women with severe VLP who successfully achieved remission using off-label treatment with the interleukin-23 (IL-23) monoclonal antibody blocker tildrakizumab, and highlight tildrakizumab as a treatment for women with recalcitrant VLP who have failed more conservative treatments.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff137f99bdd0b4750eef9e4a5ad0439b https://doi.org/10.1111/ajd.13793 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.